Calcium Citrate Tribasic Tetrahydrate: An In-Depth Product Description

Calcium citrate tribasic tetrahydrate is a unique calcium salt of citric acid, with the chemical formula C6H6Ca3O14⋅4H2OC_6H_6Ca3O_{14}\cdot 4H_2OC6​H6​Ca3O14​⋅4H2​O. This compound is a popular choice in dietary supplements and various industrial applications due to its excellent bioavailability and solubility properties. Calcium citrate tribasic tetrahydrate is particularly valued for its role in ensuring adequate calcium intake, contributing to bone health and overall wellness. This comprehensive product description will delve into the properties, applications, benefits, and safety considerations of calcium citrate tribasic tetrahydrate, emphasizing its importance across different sectors.

Chemical Properties

Composition and Structure

Calcium citrate tribasic tetrahydrate consists of three calcium ions, one citrate ion, and four water molecules, making it a highly hydrated form of calcium citrate. This structure enhances its solubility in water and its bioavailability for absorption in the body.

Physical Characteristics

• Appearance: White to off-white crystalline powder
• Molecular Weight: Approximately 498.17 g/mol
• Solubility: Highly soluble in water
• Melting Point: Decomposes rather than melting at high temperatures

These properties make calcium citrate tribasic tetrahydrate suitable for a wide range of applications in health, nutrition, and industry.

Applications of Calcium Citrate Tribasic Tetrahydrate

1. Dietary Supplements

One of the primary uses of calcium citrate tribasic tetrahydrate is in dietary supplements. It is a popular source of calcium for individuals seeking to improve their calcium intake. Its high bioavailability makes it an excellent option for those with specific dietary needs, including postmenopausal women, individuals with lactose intolerance, and vegetarians.

2. Bone Health Products

Due to its role in calcium supplementation, calcium citrate tribasic tetrahydrate is commonly included in formulations aimed at promoting bone health. It helps prevent osteoporosis and supports overall skeletal strength, making it a vital ingredient in various bone health products.

3. Food Fortification

Calcium citrate tribasic tetrahydrate is used in the food industry for fortifying products with calcium. It is often added to beverages, cereals, and dairy products to enhance their nutritional value and help prevent calcium deficiency in consumers.

4. Pharmaceuticals

In the pharmaceutical industry, calcium citrate tribasic tetrahydrate serves as a calcium source in formulations of medications and supplements. Its solubility and bioavailability make it an ideal choice for ensuring effective calcium delivery in various therapeutic applications.

5. Industrial Applications

Beyond health and nutrition, calcium citrate tribasic tetrahydrate finds applications in the industrial sector, including:

• Food Additives: Used as a stabilizer and emulsifier in processed foods.
• Cosmetics: Incorporated into cosmetic formulations for its moisturizing properties and as a pH adjuster.

Advantages of Using Calcium Citrate Tribasic Tetrahydrate

1. High Bioavailability

One of the significant advantages of calcium citrate tribasic tetrahydrate is its high bioavailability. This means that the body can absorb and utilize the calcium more efficiently compared to other forms, such as calcium carbonate. This is particularly beneficial for individuals who may have absorption issues.

2. Gentle on the Stomach

Calcium citrate tribasic tetrahydrate is less likely to cause gastrointestinal discomfort than other calcium supplements. It can be taken with or without food, making it a convenient option for many users.

3. Versatility

The diverse applications of calcium citrate tribasic tetrahydrate highlight its versatility. Whether used in dietary supplements, food fortification, or industrial applications, its effectiveness across multiple sectors makes it an indispensable resource.

4. Safe and Natural

Calcium citrate tribasic tetrahydrate is generally recognized as safe (GRAS) for consumption and is derived from natural sources. This makes it a preferred choice for consumers seeking clean-label products.

How to Use Calcium Citrate Tribasic Tetrahydrate

1. As a Dietary Supplement

When using calcium citrate tribasic tetrahydrate in dietary supplements:

• Dosage: Follow the manufacturer’s recommended dosage. Typical daily doses range from 500 mg to 1500 mg, depending on individual needs.
• Administration: It can be taken with or without food. However, taking it with meals may enhance absorption.

2. In Food Fortification

For food applications:

• Incorporation: Calcium citrate tribasic tetrahydrate can be added to food products during processing. Ensure that it is evenly distributed to achieve the desired nutritional value.
• Regulatory Compliance: Follow food safety regulations when fortifying products to ensure compliance with local and international standards.

3. In Pharmaceuticals

When used in pharmaceutical formulations:

• Preparation: Use calcium citrate tribasic tetrahydrate according to specific protocols for ensuring the correct dosage and efficacy.
• Stability Testing: Conduct stability tests to ensure that formulations maintain their integrity over time.

4. In Industrial Applications

For industrial use:

• Mixing: Incorporate calcium citrate tribasic tetrahydrate into formulations as required. Ensure proper blending to achieve uniform distribution.
• Quality Control: Regularly monitor quality to ensure compliance with industry standards.

Safety and Handling

1. Toxicity

Calcium citrate tribasic tetrahydrate is generally considered safe when used as directed. However, excessive consumption may lead to hypercalcemia, which can cause various health issues.

2. Protective Measures

When handling calcium citrate tribasic tetrahydrate, it is essential to:

• Wear Protective Gear: Use gloves and goggles to minimize exposure to dust during handling.
• Ensure Ventilation: Work in a well-ventilated area to avoid inhalation of fine particles.

3. Storage

Store calcium citrate tribasic tetrahydrate in a cool, dry place, away from direct sunlight and moisture. Ensure that containers are tightly sealed to maintain product integrity.

Environmental Considerations

Calcium citrate tribasic tetrahydrate is considered environmentally friendly, but proper disposal methods should be followed to minimize any potential impact. Always adhere to local regulations regarding chemical waste disposal.

Conclusion

Calcium citrate tribasic tetrahydrate is a versatile and valuable compound utilized across various industries, including dietary supplements, food fortification, pharmaceuticals, and industrial applications. Its unique properties, such as high bioavailability and gentle nature on the stomach, make it an essential resource for health-conscious consumers and professionals alike.

When purchasing calcium citrate tribasic tetrahydrate, choose reputable suppliers that provide high-quality products and detailed safety data sheets. Understanding its applications, benefits, and safety measures will help you maximize the potential of this remarkable compound in your projects.

Whether you’re a health professional seeking effective calcium supplements, a food manufacturer looking to enhance product quality, or an industrial expert aiming to improve formulations, calcium citrate tribasic tetrahydrate can meet your needs. Embrace the advantages of this compound and unlock new possibilities in your field!